• Biology, Medicine
  • Published in
    Cellular & molecular…
    2006

DC-SIGN and immunoregulation.

@article{Zhou2006DCSIGNAI,
  title={DC-SIGN and immunoregulation.},
  author={Tong Zhou and Yongxi Chen and Li Hao and Yanyun Zhang},
  journal={Cellular & molecular immunology},
  year={2006},
  volume={3 4},
  pages={
          279-83
        }
}
Dendritic cells (DCs) are known to be the most powerful professional antigen-presenting cells so far. It could activate primary immune response, and also downregulate immune response. DCs have a unique character of immunoregulation. DC-SIGN, a molecule designated as CD209, is one member of the C-type lectin superfamily. It is not only a pattern recognition receptor but implicated in immunoregulation of DCs. DC-SIGN has become hotspot of recent studies because of its important role in mediating… CONTINUE READING

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