DASH-2: flexible, low-cost, and high-throughput SNP genotyping by dynamic allele-specific hybridization on membrane arrays.

@article{Jobs2003DASH2FL,
  title={DASH-2: flexible, low-cost, and high-throughput SNP genotyping by dynamic allele-specific hybridization on membrane arrays.},
  author={Magnus Jobs and W. Mathias Howell and Linda Stromqvist and Torsten Mayr and Anthony J. Brookes},
  journal={Genome research},
  year={2003},
  volume={13 5},
  pages={916-24}
}
Genotyping technologies need to be continually improved in terms of their flexibility, cost-efficiency, and throughput, to push forward genome variation analysis. To this end, we have leveraged the inherent simplicity of dynamic allele-specific hybridization (DASH) and coupled it to recent innovations of centrifugal arrays and iFRET. We have thereby created a new genotyping platform we term DASH-2, which we demonstrate and evaluate in this report. The system is highly flexible in many ways (any… CONTINUE READING

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