D8S7 is consistently deleted in inverted duplications of the short arm of chromosome 8 (inv dup 8p)

Abstract

Ten patients with inverted duplication of 8p (inv dup 8p) were studied with cytogenetic, biochemical and molecular techniques. The duplication for the region 8p12-p22 was always associated with a deletion of the locus D8S7 (mapped in 8p23.1) as demonstrated with the probe pSW50 by both in situ hybridization and Southern blot. Restriction fragment length… (More)
DOI: 10.1007/BF01247342

Topics

6 Figures and Tables