D2O as a substitute for 3H2O, as a reference indicator in liver multiple-indicator dilution studies.

@article{Pang1991D2OAA,
  title={D2O as a substitute for 3H2O, as a reference indicator in liver multiple-indicator dilution studies.},
  author={K Sandy Pang and N N Xu and Carl Arthur Goresky},
  journal={The American journal of physiology},
  year={1991},
  volume={261 6 Pt 1},
  pages={G929-36}
}
The hepatic space of distribution and the processes underlying uptake of tracer substrate may be appraised by the multiple-indicator dilution technique after simultaneous injection of noneliminated vascular (51Cr-labeled red blood cells), extracellular 125I-labeled albumin and [14C]sucrose (or [58Co]EDTA) as high- and low-molecular-weight interstitial references, respectively], and cellular (3H2O or [14C]urea) indicators, together with the tracer-labeled substrate. The use of 3H2O or [14C]urea… CONTINUE READING

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