D1 and D2 dopamine receptor mRNA in rat brain.

  title={D1 and D2 dopamine receptor mRNA in rat brain.},
  author={David M. Weiner and Allan I. Levey and Roger K Sunahara and Hyman B. Niznik and Brian F O'dowd and philip. seeman and Mark R. Brann},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={88 5},
Physiological and pharmacological criteria have divided dopamine receptors into D1 and D2 subtypes, and genes encoding these subtypes have recently been cloned. Based on the sequences of the cloned receptors, we prepared oligodeoxynucleotide probes to map the cellular expression of the corresponding mRNAs in rat brain by in situ hybridization histochemistry. These mRNAs showed largely overlapping yet distinct patterns of expression. The highest levels of expression for both mRNAs were observed… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 92 extracted citations

Similar Papers

Loading similar papers…