D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs.

Abstract

The efficacy of the D1/5 agonist SKF38393 (100nM-60microM) to increase long-term potentiation (LTP) in the CA1 region was investigated in the rat hippocampal slice preparation. The receptor specificity of this enhancing effect was confirmed using the D1/5 antagonist SKF83566 (2microM). Although the ability of D1/5 receptors to increase both the persistence… (More)
DOI: 10.1016/j.neuropharm.2008.06.053

Topics

7 Figures and Tables

Cite this paper

@article{Stramiello2008D15RE, title={D1/5 receptor-mediated enhancement of LTP requires PKA, Src family kinases, and NR2B-containing NMDARs.}, author={Michael Stramiello and John J. Wagner}, journal={Neuropharmacology}, year={2008}, volume={55 5}, pages={871-7} }