D-optimal design of b-values for accurate intra-voxel incoherent motion imaging

@article{Sansone2016DoptimalDO,
  title={D-optimal design of b-values for accurate intra-voxel incoherent motion imaging},
  author={M. Sansone and R. Fusco and A. Petrillo},
  journal={arXiv: Medical Physics},
  year={2016}
}
The aim of this paper is to optimally design the set of b-values for diffusion weighted MRI with the aim of accurate estimation of intra- voxel incoherent motion (IVIM) parameters (f perfusion fraction, Ds slow diffusion, Df fast diffusion) according to the model developed by Le Bihan. Previous studies have addressed the design in a Monte Carlo fash- ion. Due to huge computation times, this approach is feasible only for a limited number of values of the parameters (local design): however, as… Expand

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