D-dimer threshold increase with pretest probability unlikely for pulmonary embolism to decrease unnecessary computerized tomographic pulmonary angiography.

@article{Kline2012DdimerTI,
  title={D-dimer threshold increase with pretest probability unlikely for pulmonary embolism to decrease unnecessary computerized tomographic pulmonary angiography.},
  author={Jeffrey A. Kline and Melanie M Hogg and Daniel Mark Courtney and Chadwick D Miller and Alan E. Jones and Howard A. Smithline},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2012},
  volume={10 4},
  pages={572-81}
}
BACKGROUND Increasing the threshold to define a positive D-dimer could reduce unnecessary computed tomographic pulmonary angiography (CTPA) for a suspected pulmonary embolism (PE) but might increase rates of a missed PE and missed pneumonia, the most common non-thromboembolic diagnosis seen on CTPA. OBJECTIVE Measure the effect of doubling the standard D-dimer threshold for 'PE unlikely' Revised Geneva (RGS) or Wells' scores on the exclusion rate, frequency and size of a missed PE and missed… CONTINUE READING
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Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism

  • C Kabrhel, C Mark, +7 authors JA. Kline
  • Acad Emerg Med
  • 2010

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