D-amino acids in the brain: the biochemistry of brain serine racemase.

@article{Baumgart2008DaminoAI,
  title={D-amino acids in the brain: the biochemistry of brain serine racemase.},
  author={Florian Baumgart and Ignacio Rodr{\'i}guez-Crespo},
  journal={The FEBS journal},
  year={2008},
  volume={275 14},
  pages={3538-45}
}
It has been recently established that in various brain regions D-serine, the product of serine racemase, occupies the so-called 'glycine site' within N-methyl D-aspartate receptors. Mammalian brain serine racemase is a pyridoxal-5' phosphate-containing enzyme that catalyzes the racemization of L-serine to D-serine. It has also been shown to catalyze the alpha,beta-elimination of water from L-serine or D-serine to form pyruvate and ammonia. Serine racemase is included within the group of type II… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…