D-Glucosamine-induced increase of the glycerol-containing lipids in growing cultures of human malignant epithelial cells.
@article{Krug1983DGlucosamineinducedIO,
title={D-Glucosamine-induced increase of the glycerol-containing lipids in growing cultures of human malignant epithelial cells.},
author={Eva Krug and Elisabeth Dussaulx and Raymond Rozen and Sabine Griglio and P de Gasquet and Alain Zweibaum},
journal={Journal of the National Cancer Institute},
year={1983},
volume={70 1},
pages={
57-61
}
}D-Glucosamine was found to inhibit the growth of human malignant epithelial cells SW-839, HT-29, RT-4, and SK-OV-3 in culture in a process that was associated with significant increments in glycerol-containing lipids. Each cell line had a different sensitivity to the drug, but all four cell lines shared the same features in their response, i.e., dose-dependent (at concentrations of 1, 5, and 10 mM), noncytotoxic reductions in growth (minimum 30%, maximum 70%), and simultaneous 1.5-fold to…
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