D-Dimer and Inflammatory Markers as Predictors of Functional Decline in Men and Women with and without Peripheral Arterial Disease

@article{McDermott2005DDimerAI,
  title={D-Dimer and Inflammatory Markers as Predictors of Functional Decline in Men and Women with and without Peripheral Arterial Disease},
  author={Mary M McDermott and Luigi Ferrucci and K. -L. Liu and Michael H. Criqui and Philip Greenland and David Vincent Green and Jack Guralnik and Paul M. Ridker and Lloyd M. Taylor and N M El Rifai and Lu Tian and Jane Zheng and William H. Pearce and Joseph R. Schneider and Ed Vonesh},
  journal={Journal of the American Geriatrics Society},
  year={2005},
  volume={53 10},
  pages={1688-96}
}
OBJECTIVES To determine whether higher circulating levels of inflammatory and thrombotic markers are associated with greater decline in lower extremity performance. DESIGN Prospective cohort. SETTING Academic medical center. PARTICIPANTS Three hundred thirty-seven men and women with lower extremity peripheral arterial disease (PAD) and 215 without PAD. MEASUREMENTS Objective measures of leg function, including the 6-minute walk and Short Physical Performance Battery (SPPB), were… CONTINUE READING

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