D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data.

@article{MataixCols2017DCycloserineAO,
  title={D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data.},
  author={David Mataix-Cols and Lorena Fern{\'a}ndez de la Cruz and Benedetta A Monzani and David Rosenfield and Erik Andersson and Ana P{\'e}rez-Vigil and Paolo Frumento and Rianne A. de Kleine and JoAnn Difede and Boadie W. Dunlop and Lara J Farrell and Dave Geller and Maryrose Gerardi and Adam J Guastella and Stefan G. Hofmann and Gert-Jan Hendriks and Matt G. Kushner and Francis B. S. Lee and Eric J. Lenze and Cheri A Levinson and Harry W McConnell and Michael W Otto and Jens Plag and Mark H. Pollack and Kerry J. Ressler and Thomas L. Rodebaugh and Barbara O. Rothbaum and Michael S. Scheeringa and Anja Siewert-Siegmund and Jasper A J Smits and Eric A. Storch and Andreas Str{\"o}hle and Candyce D Tart and David F. Tolin and M Verhagen and Allison M Waters and Carl F. Weems and Sabine Wilhelm and Katarzyna E. Wyka and Michael Davis and Christian R{\"u}ck and Margaret Altemus and Page Anderson and Judith Cukor and Claudia Finck and Gary R. Geffken and Fabian Golfels and Wayne K. Goodman and Cassidy A Gutner and Isobel Heyman and Tanja Jovanovic and Adam B. Lewin and Joseph McNamara and Tanya K. Murphy and Seth D. Norrholm and Paul D. Thuras},
  journal={JAMA psychiatry},
  year={2017},
  volume={74 5},
  pages={501-510}
}
Importance Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclear. Objective To clarify whether DCS is superior to placebo in augmenting the effects of cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to evaluate whether antidepressants interact with DCS and the effect of potential moderating… CONTINUE READING