D-Amphetamine remediates attentional performance in rats with dorsal prefrontal lesions.

  title={D-Amphetamine remediates attentional performance in rats with dorsal prefrontal lesions.},
  author={Yogita Chudasama and Falguni Nathwani and Trevor W. Robbins},
  journal={Behavioural brain research},
  volume={158 1},
Although amphetamine treatment has been shown to promote recovery of motor function in animals with cortical ablations, the potential therapeutic effect of amphetamine on processes other than motor control, such as attention and working memory, has been relatively unexplored. Accordingly, we investigated the beneficial effect of D-amphetamine treatment in animals with dorsal prefrontal cortex lesions (dPFC) compared with sham controls on a novel combined attention-memory task (CAM) that… CONTINUE READING

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