Déjà vu in neurology

  title={D{\'e}j{\`a} vu in neurology},
  author={Edward Wild},
  journal={Journal of Neurology},
  • E. Wild
  • Published 2005
  • Psychology, Medicine
  • Journal of Neurology
The significance of déjà vu is widely recognised in the context of temporal lobe epilepsy, and enquiry about déjà vu is frequently made in the clinical assessment of patients with possible epilepsy. Déjà vu has also been associated with several psychiatric disorders. The historical context of current understanding of déjà vu is discussed. The literature reveals déjà vu to be a common phenomenon consistent with normality. Several authors have suggested the existence of a “pathological” form of d… 
Déjà Experiences in Temporal Lobe Epilepsy
A decoupled familiarity hypothesis is proposed, whereby déjà vu is produced by an erroneous feeling of familiarity which is not in keeping with current cognitive processing, and a parahippocampal dysfunction as the locus of déjaa vu experiences is converged on.
Persistent déjà vu associated with temporal lobe epilepsy in an adolescent.
An adolescent diagnosed with temporal lobe epilepsy who experienced persistent déjà vu at a young age is described, which presents an interesting finding, as it shows that young adolescents are able to describe in detail an aura such as déjaa vu that will allow physicians to identify the disorder much earlier.
Temporal Lobe Epilepsy (TLE) , “déjà vu” phenomenon and religious experiences
A lot of controversies appear regarding temporal lobe epilepsy to bridge the gap between religion and neuroscience. TLE was described in literature in 1869 by Russian writer Dostoievski (who suffered
Déjà vu and prescience in a case of severe episodic amnesia following bilateral hippocampal lesions
This study shows that déjà vu can occur in cases of amnesia with massively damaged hippocampi and confirms that the perirhinal region is a core region for déjé vu, using a different approach from previous reports.
Neural Correlates of Deja Vu and Dissociation: The Roles of the Amygdala and Hippocampus in the Prevalence of Deja Vu Used as an Indicator for the Severity of Dissociation and Posttraumatic Stress Disorder
This study demonstrated through correlational analyses that there are significant relationships between components of each that can be utilized to aid in determining the likely-hood of PTSD and dissociative symptoms.
Migraine and Epilepsy: A Focus on Overlapping Clinical, Pathophysiological, Molecular, and Therapeutic Aspects
The relationship between migraine and epilepsy is reviewed, focusing on clinical aspects and some recent pathophysiological and molecular studies.
Uncommon and/or bizarre features of dementia. Part II
Describing uncommon or bizarre symptoms/syndromes observed in patients suffering from dementia as case reports and there were no systematic investigations are described.
Contribution of amygdala pathology to comorbid emotional disturbances in temporal lobe epilepsy
Experimental and human positron emission tomography studies indicate changes in amygdala serotonergic, NPY Y1 receptor, neurokinin, and opioid systems in emotional disturbances in TLE, suggesting a differential role of TLE‐related amygdala changes in ictal and interictal emotional disturbances.


Déjà vu in psychiatric and neurosurgical patients.
Reminiscence of this type being described by such nonscientists as Tennyson, Coleridge, and, as above, Dickens is mentioned.
The déjà vu experience: remembrance of things past?
The authors discuss the epidemiologic data, clinical features, and etiology of the phenomenon of déjà vu, and introduce an explanation based on the hologram as a mnestic model.
Interictal 18FDG PET findings in temporal lobe epilepsy with déjà vu.
It is suggested that extensive association cortical areas may be involved as part of the network that integrates this distinct experience in déjà vu and that temporal lobe dysfunction is necessary but not sufficient for the generation of DV.
Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features
Discovery of LGI1 as a cause of ADPEAF suggests new avenues for research on pathogenic mechanisms of idiopathic epilepsies and shows that the expression pattern of mouse Lgi1 is predominantly neuronal and is consistent with the anatomic regions involved in temporal lobe epilepsy.
Long‐Term Subdural Strip Electrocorticographic Monitoring of Ictal Déjà Vu
Although ictal déjà vu localizes the epileptic focus to temporal lobe, this experiential phenomenon appears to lateralize to the hemisphere nondominant for handedness.
Le “déjà vu”: élaboration d’un modèle d’approche hypothétique
Although psychiatric literature abounds in allusions to the phenomenon of ‘dEjA vu’, few communications were devoted to an analysis of this interesting psychological state. After a short review of
Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy.
It is demonstrated that the LGI1 protein, which contains several leucine-rich repeats, is expressed ubiquitously in the neuronal cell compartment of the brain and provides evidence for genetic heterogeneity within this disorder.
Familial temporal lobe epilepsy Autosomal dominant inheritance in a large pedigree from Southern Italy
Experiential phenomena of temporal lobe epilepsy. Facts and hypotheses.
  • P. Gloor
  • Psychology, Biology
    Brain : a journal of neurology
  • 1990
Arguments are presented which indicate that experiential phenomena are positive expressions of temporal lobe and limbic function and do not result from its ictal paralysis, and the hypothesis assumes that temporal lobe epileptic discharge or electrical stimulation ofporal lobe structures can induce the elaboration of patterns of excitation and inhibition in widely distributed neuronal networks.
Autosomal dominant partial epilepsy with auditory features: Defining the phenotype
Auditory hallucinations, the most striking clinical feature, are useful for identifying new families with this synome and the clinical semiology points to a lateral temporal seizure origin.