Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells.

@article{Kuete2016CytotoxicityOS,
  title={Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells.},
  author={Victor Kuete and Armelle T. Mbaveng and Eric C N Nono and Christophe C.F. Simo and Maen Zeino and Augustin Ephraim Nkengfack and Thomas Efferth},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2016},
  volume={23 8},
  pages={
          856-63
        }
}
  • V. Kuete, A. Mbaveng, +4 authors T. Efferth
  • Published 2016
  • Chemistry, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
INTRODUCTION In medical oncology, multi-drug resistance (MDR) of cancer cells continues to be a major impediment. We are in quest of novel anti-proliferative agents to overcome drug-resistant tumor cells. METHODS In the present study, we investigated the cytotoxicity of 7 naturally occurring phenolic compounds including two isoflavonoids alpinumisoflavone (1) and laburnetin (2), one biflavonoid amentoflavone (3), three lignans pycnanthulignene A (4), pycnanthulignene B (5), and syringaresinol… Expand
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