Cytotoxicity of pregnane glycosides of Cynanchum otophyllum.

  title={Cytotoxicity of pregnane glycosides of Cynanchum otophyllum.},
  author={Mi Zhang and Xiang Li and Cheng Xiang and Yi Qin and Jing Jing He and Bao-cai Li and Peng Li},
Fourteen new pregnane glycosides, including nine caudatin glycosides (1-9), three qinyangshengenin glycosides (10-12), one kidjoranin glycosides (13) and one gagaminin glycosides (14), along with twelve known analogs (15-26) were isolated from roots of Cynanchum otophyllum Schneid. Their structures were deduced by detailed analysis of 1D and 2D NMR spectra, as well as HRESIMS. In this study, all pregnane glycosides obtained (1-26) were evaluated for their cytotoxic activities using three cancer… CONTINUE READING