Cytotoxicity of intracameral injection drugs to corneal endothelium as evaluated by corneal endothelial cell culture.

@article{Chang1995CytotoxicityOI,
  title={Cytotoxicity of intracameral injection drugs to corneal endothelium as evaluated by corneal endothelial cell culture.},
  author={C H Chang and Charles P. Lin and Hongyan Wang},
  journal={Cornea},
  year={1995},
  volume={14 1},
  pages={
          71-6
        }
}
The cell culture method was used to quantitatively evaluate the cytotoxicity to porcine corneal endothelial cells by drugs in the usual concentrations of intracameral injections (ICI). Time-dependent cytotoxicity of drugs was evaluated quantitatively; dye exclusion assay by trypan blue was used as a viability assay; and cytotoxicity to corneal endothelium was tested using amphotericin-B, amikacin, colistin, sulbenicillin, and cephradine in their original, 10-fold, and 100-fold ICI… CONTINUE READING
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