• Biology
  • Published 2010

Cytotoxicity of cytokine-induced killer cells targeted by the bispecific antibody anti-CD3xanti-AFP on AFP positive hepatoma cells

@inproceedings{Jian2010CytotoxicityOC,
  title={Cytotoxicity of cytokine-induced killer cells targeted by the bispecific antibody anti-CD3xanti-AFP on AFP positive hepatoma cells},
  author={Xu Yu Jian},
  year={2010}
}
Purpose To establish the method in which CIK cells targeted by the bispecific antibody anti-CD3xanti-AFP specifically lyse AFP positive hepatoma cells.Methods CIK cells were activated by anti-CD3 antibody and IL-2 from human peripheral blood lymphocytes and cell phenotypes were detected by flow cytometer.Gold colloid was prepared by the method of citric acid tri-sodium revert,bispecific colloidal gold antibody anti-CD3xanti-AFP were prepared by physical adsorption,and activities of antibodies… CONTINUE READING