Cytotoxicity and genotoxicity of lipid-oxidation products.

@article{Esterbauer1993CytotoxicityAG,
  title={Cytotoxicity and genotoxicity of lipid-oxidation products.},
  author={Hermann Esterbauer},
  journal={The American journal of clinical nutrition},
  year={1993},
  volume={57 5 Suppl},
  pages={
          779S-785S; discussion 785S-786S
        }
}
  • H. Esterbauer
  • Published 1 May 1993
  • Biology
  • The American journal of clinical nutrition
The autoxidation of unsaturated lipids contained in oils, fats, and food and the endogenous oxidative degradation of membrane lipids by lipid peroxidation result in the formation of a very complex mixture of lipid hydroperoxides, chain-cleavage products, and polymeric material. Experimental animal studies and biochemical investigations lend support to the hypothesis that lipid-oxidation products, ingested with food or produced endogenously, represent a health risk. The oral toxicity of oxidized… 

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