Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone.

@article{AbidEssefi2004CytotoxicityIO,
  title={Cytotoxicity, inhibition of DNA and protein syntheses and oxidative damage in cultured cells exposed to zearalenone.},
  author={Salwa Abid-Essefi and Zouhour Ouanes and Wafa Hassen and Isabelle Baudrimont and Edmond Eku{\'e} Creppy and Hassen Bacha},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2004},
  volume={18 4},
  pages={467-74}
}
Mycotoxins are toxic metabolites of various fungi commonly found in feed and foodstuff and can cause very serious health problems in animals as well as in humans. Zearalenone (ZEN), a mycotoxin produced by various Fusarium species has several adverse effects. Indeed, ZEN has strong estrogenic activity associated with hyperestrogenism and several physiological alterations of the reproductive tract. Moreover, ZEN was shown to be hepatotoxic, haematotoxic, immunotoxic and genotoxic. The exact… CONTINUE READING

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