Cytotoxicity, genotoxicity and antibacterial effectiveness of a bioceramic endodontic sealer.

@article{Candeiro2016CytotoxicityGA,
  title={Cytotoxicity, genotoxicity and antibacterial effectiveness of a bioceramic endodontic sealer.},
  author={George T{\'a}ccio de Miranda Candeiro and Cacio Moura-Netto and Roberta Souza D'Almeida-Couto and N Azambuja-J{\'u}nior and M{\'a}rcia M Marques and Silvana Cai and Giulio Gavini},
  journal={International endodontic journal},
  year={2016},
  volume={49 9},
  pages={
          858-864
        }
}
AIM To compare the characteristics of bioceramic endodontic sealer Endosequence BC sealer with those of AH Plus sealer. METHODOLOGY Cytotoxicity and genotoxicity were analysed on human gingival fibroblasts submitted to cell culture medium conditioned by sealers using the MTT reduction assay and micronucleus formation test (MNT), respectively. Cells grown on fresh medium served as controls. Cell viabilities were measured at 1, 3, 5 and 7 days. The antibacterial activity was analysed on an… CONTINUE READING