Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.
@article{Cao2004CytotoxicTF, title={Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.}, author={Shugeng Cao and Rebecca Clare Guza and James Stuart Miller and Rabodo Andriantsiferana and Vincent Emile Rasamison and David G I Kingston}, journal={Journal of natural products}, year={2004}, volume={67 6}, pages={ 986-9 } }
Bioassay-guided fractionation of the cytotoxic MeOH extract obtained from Acridocarpus vivy led to the isolation of five new triterpenoids, acridocarpusic acids A-E (1-5); three known triterpenoids, moronic acid (6), ursolic acid, and oleanolic acid; and two known flavonoids, 4',5-dihydroxy-7-methoxyflavone and 4',5-dihydroxy-3',7-dimethoxyflavone. The structures of the new compounds 1-5 were established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Compound 3…
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