Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.

  title={Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.},
  author={Shugeng Cao and R. Guza and J. S. Miller and Rabodo Andriantsiferana and V. Rasamison and D. Kingston},
  journal={Journal of natural products},
  volume={67 6},
  • Shugeng Cao, R. Guza, +3 authors D. Kingston
  • Published 2004
  • Biology, Medicine
  • Journal of natural products
  • Bioassay-guided fractionation of the cytotoxic MeOH extract obtained from Acridocarpus vivy led to the isolation of five new triterpenoids, acridocarpusic acids A-E (1-5); three known triterpenoids, moronic acid (6), ursolic acid, and oleanolic acid; and two known flavonoids, 4',5-dihydroxy-7-methoxyflavone and 4',5-dihydroxy-3',7-dimethoxyflavone. The structures of the new compounds 1-5 were established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Compound 3… CONTINUE READING
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