Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.

@article{Cao2004CytotoxicTF,
  title={Cytotoxic triterpenoids from Acridocarpus vivy from the Madagascar rain forest.},
  author={Shugeng Cao and Rebecca Clare Guza and James Stuart Miller and Rabodo Andriantsiferana and Vincent Emile Rasamison and David G I Kingston},
  journal={Journal of natural products},
  year={2004},
  volume={67 6},
  pages={
          986-9
        }
}
Bioassay-guided fractionation of the cytotoxic MeOH extract obtained from Acridocarpus vivy led to the isolation of five new triterpenoids, acridocarpusic acids A-E (1-5); three known triterpenoids, moronic acid (6), ursolic acid, and oleanolic acid; and two known flavonoids, 4',5-dihydroxy-7-methoxyflavone and 4',5-dihydroxy-3',7-dimethoxyflavone. The structures of the new compounds 1-5 were established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Compound 3… CONTINUE READING
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