Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis.
@article{Wang2011CytotoxicTS,
title={Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis.},
author={Xiao-yang Wang and Xiao-Li Chen and Hai-Feng Tang and Hui Gao and Xiang-rong Tian and Ping-Hu Zhang},
journal={Planta medica},
year={2011},
volume={77 13},
pages={
1550-4
}
}Two new oleanane-type triterpenoid saponins, 1 and 2, and a new natural product, 3, together with five known saponins, 4- 8, were isolated from the rhizomes of ANEMONE TAIPAIENSIS. Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Six saponins, 1, 2, 4- 7, which possessed a free carboxylic group at C-28, exhibited significant cytotoxicity against human leukemia HL-60 cells and human hepatocellular carcinoma Hep-G2 cells with IC (50) values in the range…
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