Cytotoxic steroids from Polyporus umbellatus.

  title={Cytotoxic steroids from Polyporus umbellatus.},
  author={Ying-Yong Zhao and Xu Chao and Yongmin Zhang and Ruichao Lin and Wen-ji Sun},
  journal={Planta medica},
  volume={76 15},
The steroids ergone (1), (22E, 24R)-ergosta-7,22-dien-3β-ol (2), 5α,8α-epidioxy-(22E,24R) -ergosta-6,22-dien-3β-ol (3), ergosta-6,22-dien-3β,5α,6β-triol (4), and polyporusterone B (5) were isolated from Polyporus umbellatus by bioassay-guided approach. They showed potent anticancer activity against HepG2 cells. Ergone displayed remarkable anticancer activity against HepG2, Hep-2, and Hela cancer cells, of which HepG2 cells were the most sensitive. Furthermore, the cytotoxic effects of ergone on… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
17 Citations
21 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 21 references

Cytotoxic Steroids from.

  • Zhao Y-Y
  • Planta Med
  • 2010

performance liquid chromatography coupled with mass spectrometry detections

  • YY Zhao, Y Zhao, YM Zhang, RC Lin, WJ. Sun
  • Biomed Chromatogr
  • 2010

Cytotoxic activity of ergosta-4,6, 8(14),22‐tetraen-3-one from the sclerotia of Polyporus umbellatus

  • J umbellatus
  • Ethnopharmacol
  • 2009

Xylaria sp. possessing inhibitory activity of nitric oxide production

  • H Fujimoto, E Nakamura, E Okuyama, M. Ishibashi
  • Nat Prod Res
  • 2008

Similar Papers

Loading similar papers…