Cytotoxic spirostane-type saponins from the roots of Chlorophytum borivilianum.

@article{Acharya2009CytotoxicSS,
  title={Cytotoxic spirostane-type saponins from the roots of Chlorophytum borivilianum.},
  author={Debabrata Acharya and Anne-Claire Mitaine-Offer and Nutan Kaushik and Tomofumi Miyamoto and Thomas Paululat and Jean François Mirjolet and Olivier Duchamp and Marie‐Aleth Lacaille‐Dubois},
  journal={Journal of natural products},
  year={2009},
  volume={72 1},
  pages={
          177-81
        }
}
Four new spirostane-type saponins named borivilianosides E-H (1-4) were isolated from an ethanol extract of the roots of Chlorophytum borivilianum together with two known steroid saponins (5 and 6). The structures of 1-4 were elucidated using mainly 2D NMR spectroscopic techniques and mass spectrometry. The cytotoxicity of borivilianosides F (2), G (3), and H (4) and three known compounds was evaluated using two human colon cancer cell lines (HT-29 and HCT 116). 

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