Cytotoxic sphingosine 4-sulfates from the sponge Spirastrella abata.

Abstract

Two new sphingosine 4-sulfates (1 and 2) have been isolated from the sponge Spirastrella abata as cytotoxic constituents. The gross structures of 1 and 2 were determined by spectroscopic analysis, and their stereochemistry was established by chemical conversion. The compounds exhibited significant cytotoxicity against a small panel of five human tumor cell lines.

Cite this paper

@article{Alam2002CytotoxicS4, title={Cytotoxic sphingosine 4-sulfates from the sponge Spirastrella abata.}, author={Naseer Alam and Weihong wang and Jongki Hong and Chong-Ok Lee and Kwang Sik Im and Jee Hyung Jung}, journal={Journal of natural products}, year={2002}, volume={65 6}, pages={944-5} }