Cytotoxic properties of eosinophil granule major basic protein for tumor cells.

Abstract

BACKGROUND Eosinophil granule major basic protein (MBP) mediates many eosinophil-associated immune functions and it adheres eosinophils to parasite targets. METHODS We compared the toxicities of MBP and melittin to K562 and HL-60 cells using five cytotoxicity methods. RESULTS Trypan blue staining, propidium iodide/ CellTrackertrade markGreen staining… (More)

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