Cytotoxic polyketides from a marine-derived fungus Aspergillus glaucus.

  title={Cytotoxic polyketides from a marine-derived fungus Aspergillus glaucus.},
  author={Lin Du and Tianjiao Zhu and Hongbing Liu and Yuchun Fang and Weiming Zhu and Qianqun Gu},
  journal={Journal of natural products},
  volume={71 11},
  • L. Du, T. Zhu, Q. Gu
  • Published 6 November 2008
  • Chemistry
  • Journal of natural products
Eight new aromatic polyketides (2, 4-6, 8, 14, 16, and 17) together with eight known analogues (3, 7, 9-13, and 15) were isolated from the marine-derived fungus Aspergillus glaucus. The structures and stereochemistry of the new compounds were elucidated by spectroscopic and chemical methods, and their cytotoxicities were evaluated against the HL-60 and A-549 cell lines. 

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