Cytotoxic phloroglucinols from the leaves of Myrtus communis.

@article{Cottiglia2012CytotoxicPF,
  title={Cytotoxic phloroglucinols from the leaves of Myrtus communis.},
  author={Filippo Cottiglia and Laura Casu and Marco Leonti and Pierluigi Caboni and Costantino Floris and Bernardetta Busonera and Pamela Farci and Aicha Ouhtit and Giuseppina Sanna},
  journal={Journal of natural products},
  year={2012},
  volume={75 2},
  pages={225-9}
}
Bioactivity-guided fractionation of a dichloromethane extract of the leaves of Myrtus communis led to the isolation of phloroglucinol derivatives. The structures of the new myrtucommulones J, K, and L (1-3) and the previously known myrtucommulone A (4) were elucidated on the basis of extensive 1D and 2D NMR experiments as well as high-resolutionmass spectrometry. Myrtucommulone J was obtained as a tautomeric pair (1/1a). The compounds were tested in vitro for their cytotoxic and antibacterial… CONTINUE READING

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