• Corpus ID: 257452

Cytotoxic effects of chloroform and hydroalcoholic extracts of aerial parts of Cuscuta chinensis and Cuscuta epithymum on Hela, HT29 and MDA-MB-468 tumor cells

@article{Jafarian2014CytotoxicEO,
  title={Cytotoxic effects of chloroform and hydroalcoholic extracts of aerial parts of Cuscuta chinensis and Cuscuta epithymum on Hela, HT29 and MDA-MB-468 tumor cells},
  author={Abbas Jafarian and Alireza Ghannadi and Bahram Mohebi},
  journal={Research in Pharmaceutical Sciences},
  year={2014},
  volume={9},
  pages={115 - 122}
}
Previous studies have indicated that some species of Cuscuta possess anticancer activity on various cell lines. Due to the lack of detailed researches on the cytotoxic effects of Cuscuta chinensis and Cuscuta epithymum, the aim of the present study was to evaluate cytotoxic effects of chloroform and hydroalcoholic extracts of these plants on the human breast carcinoma cell line (MDA-MB-468), human colorectal adenocarcinoma cell line (HT29) and human uterine cervical carcinoma (Hela). Using… 

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References

SHOWING 1-10 OF 30 REFERENCES

Cytotoxicologic Studies of the Extracts of Iranian Juniperus Sabina and Platycladus Orientalis on Cancer Cells

Background: Isolation and identification of some potent anti-tumor compounds from medicinal plants, has motivated researchers to screen different parts of plant species for anti-tumor effects. It has

In Vitro Cytotoxic Effects of Cuscuta chinensis Whole Extract on Human Acute Lymphoblastic Leukemia Cell Line

The findings of the present study suggest that C. chinensis is toxic against CCRF-CEM and JM tumor cells and whether or not such effects can be employed for the treatment of such tumors must await future studies.

Evaluation of Antitumor Activity of Cuscuta Reflexa Roxb (Cuscutaceae) Against Ehrlich Ascites Carcinoma in Swiss Albino Mice

The results suggest that the chloroform and ethanol extracts of C. reflexa exhibit significant antitumor activity in EAC-bearing mice that is comparable to that of the reference standard, 5fluorouracil.

Cytotoxic effects of Cuscuta extract on human cancer cell lines

Cuscuta extract seems to be a good candidate as an anti-cancer agent against lymphoma and melanoma cancers, and Raji cells are more sensitive to Cus cuta than the SK-MEL-3 cells.

Cytotoxic Effects of Essential Oils of Some Iranian Citrus Peels

The cytotoxicity of essential oils of Iranian Citrus limon, C. medica and C. sinensis had a greater cytotoxic effect on MCF-7 than that on Hela cells, and it could be concluded that these components may have greater cytOToxic effects or they may also have synergistic effects with limonene.

Antiosteoporotic compounds from seeds of Cuscuta chinensis.

Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats.

A study of the effects of Cydonia oblonga Miller (Quince) on TNBS-induced ulcerative colitis in rats

Data suggest that QJ and QHE were effective to diminish inflammation and ulcer indices in this murine model of acute colitis, and quince fractions could be considered as a suitable anticolitic alternative, however further studies are needed to support this hypothesis.