Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest.

  title={Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar rainforest.},
  author={Venkata Sai Prakash Chaturvedula and Andrew Norris and James Stuart Miller and Fidisoa Ratovoson and Rabodo Andriantsiferana and Vincent Emile Rasamison and David G I Kingston},
  journal={Journal of natural products},
  volume={69 2},
Bioassay-directed fractionation of ethanol extracts of the roots and leaves of the plant Cassipourea madagascariensis resulted in the isolation of the two new terpenoids cassipourol (1) and cassipouryl acetate (2) in addition to the three known compounds, 3beta,30-dihydroxylup-20(29)-ene (3), 30-hydroxylup-20(29)-en-3-one (4), and combretol (5). The structures of the two new compounds were established on the basis of 1D and 2D NMR spectroscopic data and chemical conversion. All the isolated… 
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Two new sulfur-containing amides, cassipoureamide-A and -B, have been isolated from the stem wood of Cassipourea guianensis, and their structures were determined to be cis-N-(2-hydroxyethyl)-4-Hydroxy-1,2-dithiolane-3-carboxamide and cis- N-(2,2,3-trithiane-4- carboxamide, respectively.
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