Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma cell line.

@article{Kofinas1998CytotoxicCF,
  title={Cytotoxic coumarins from the aerial parts of Tordylium apulum and their effects on a non-small-cell bronchial carcinoma cell line.},
  author={Constantinos Kofinas and Loanna Chinou and Anargyros Loukis and Catherine Harvala and Christos Roussakis and Michel Maillard and Kurt Hostettmann},
  journal={Planta medica},
  year={1998},
  volume={64 2},
  pages={
          174-6
        }
}
Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asynchronous cells of the NSCLC-N6 line with a flow cytometry apparatus. 
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