Cytotoxic clerodane diterpenoids from Casearia obliqua.

  title={Cytotoxic clerodane diterpenoids from Casearia obliqua.},
  author={Gerardo Magela Vieira and Tiago de Oliveira Gonçalves and Lu{\'i}s Oct{\'a}vio Regasini and Paulo Michel Pinheiro Ferreira and Cl{\'a}udia do O Pessoa and Let{\'i}cia Veras Costa Lotufo and Roseli Buzanelli Torres and Nivaldo Boralle and Vanderlan da Silva Bolzani and Alberto Jos{\'e} Cavalheiro},
  journal={Journal of natural products},
  volume={72 10},
A crude bioactive EtOH extract of the twigs of Casearia obliqua afforded two new clerodane diterpenes, caseobliquins A (1) and B (2). Additionally, bioactivity-directed fractionation on a bioactive hexane extract of the leaves from this species led to the isolation of the known clerodane diterpenes rel-6beta-hydroxyzuelanin-2beta-benzoate and rel-2alpha… CONTINUE READING