Cytotoxic chemotherapy and the evolution of cellular and viral resistance to antiretroviral therapy in HIV- infected individuals with lymphoma.

Abstract

BACKGROUND The use of combination antiretroviral therapy (cART) and cytotoxic chemotherapy for HIV-associated lymphoma runs the risks of inducing HIV drug resistance. This study examined two possible mechanisms: altered expression of membrane drug transporter protein (MTP) and acquisition of mutations in pro-viral DNA. METHODS Expression levels of MTP and… (More)
DOI: 10.1080/15284336.2016.1210719

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Cite this paper

@article{McFaul2016CytotoxicCA, title={Cytotoxic chemotherapy and the evolution of cellular and viral resistance to antiretroviral therapy in HIV- infected individuals with lymphoma.}, author={Katie M McFaul and Neill James Liptrott and Alison E Cox and Phillip Martin and Deirdre Egan and Andrew Owen and Sarah A M Kelly and Zeenat Karolia and Kate L. Shaw and Mark Bower and Marta Boffito}, journal={HIV clinical trials}, year={2016}, volume={17 5}, pages={197-203} }