Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seeds.

@article{Swamy2000CytotoxicAI,
  title={Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seeds.},
  author={S. Swamy and B. Tan},
  journal={Journal of ethnopharmacology},
  year={2000},
  volume={70 1},
  pages={
          1-7
        }
}
  • S. Swamy, B. Tan
  • Published 2000
  • Biology, Medicine
  • Journal of ethnopharmacology
In-vitro cytotoxic screening of extracts of Nigella sativa L. seeds (Ranunculaceae) indicated cytotoxicity in the ethyl-acetate fraction (EAF) against different classes of cancer cell lines, P388, Molt4, Wehi 164, LL/2, Hep G2, SW620 and J82, as measured by 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The ethyl-acetate column chromatographic fraction (CC-5) showed selectivity against Hep G2, Molt4, and LL/2. CC-5 was relatively non-toxic against human umbilical… Expand
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