Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium

@article{Regalado2011CytotoxicAH,
  title={Cytotoxic and haemolytic steroidal glycosides from the Caribbean sponge Pandaros acanthifolium
},
  author={E. Regalado and T. Turk and D. Taşdemir and M. Gorjanc and M. Kaiser and O. Thomas and R. Fernández and P. Amade},
  journal={Steroids},
  year={2011},
  volume={76},
  pages={1389-1396}
}
Six new steroidal saponins, pandarosides K-M (1-3) and their methyl esters (4-6), were isolated as minor components, after a careful chemical reinvestigation of the Caribbean sponge Pandaros acanthifolium. Their structures were established on the basis of spectroscopic analyses and comparison with the data obtained from previous metabolites of this family. All new compounds showed moderate to weak activity against four parasitic protozoa. Additionally, these compounds and previously reported… Expand
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