Cytotoxic alkaloids from Fusarium incarnatum associated with the mangrove tree Aegiceras corniculatum.

  title={Cytotoxic alkaloids from Fusarium incarnatum associated with the mangrove tree Aegiceras corniculatum.},
  author={L. Ding and H. Dahse and C. Hertweck},
  journal={Journal of natural products},
  volume={75 4},
  • L. Ding, H. Dahse, C. Hertweck
  • Published 2012
  • Biology, Medicine
  • Journal of natural products
  • Several unusual alkaloids, N-2-methylpropyl-2-methylbutenamide (1), 2-acetyl-1,2,3,4-tetrahydro-β-carboline (2), fusarine (3), fusamine (4), and 3-(1-aminoethylidene)-6-methyl-2H-pyran-2,4(3H)-dione (5), were isolated from the culture broth of Fusarium incarnatum (HKI0504), an endophytic fungus of the mangrove plant Aegiceras corniculatum. Compounds 2, 4, and 5 exhibit weak antiproliferative and cytotoxic activities against HUVEC, K-562, and HeLa human cell lines, respectively. 
    28 Citations

    Topics from this paper

    Alkaloids from the Mangrove-Derived Actinomycete Jishengella endophytica 161111
    • 43
    • PDF
    New chlamydosporol derivatives from the endophytic fungus Fusarium sp. #001
    • 5
    Bisamides and rhamnosides from mangrove actinomycete Streptomyces sp. SZ-A15
    • 6
    Aspergiloid I, an unprecedented spirolactone norditerpenoid from the plant-derived endophytic fungus Aspergillus sp. YXf3
    • 11
    • PDF
    Plant-like Cadinane Sesquiterpenes from an Actinobacterial Mangrove Endophyte.


    Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504) isolated from the mangrove plant Aegiceras corniculatum
    • L. Li, Y. Ding, +6 authors W. Lin
    • Chemistry, Medicine
    • Journal of Asian natural products research
    • 2008
    • 22