Cytotoxic activity of the bioactive principles from Ficus burtt-davyi

@article{Ogunlaja2018CytotoxicAO,
  title={Cytotoxic activity of the bioactive principles from Ficus burtt-davyi},
  author={Olumuyiwa O. Ogunlaja and Roshila Moodley and Moganavelli Singh and H. Baijnath and Sreekantha Babu Jonnalagadda},
  journal={Journal of Environmental Science and Health, Part B},
  year={2018},
  volume={53},
  pages={261 - 275}
}
ABSTRACT Ficus burtt-davyi (Moraceae) is a medicinal plant species indigenous to Southern Africa. In this study, a phytochemical and cytotoxic investigation on F. burtt-davyi was conducted to evaluate its ethno-medicinal use. The phytochemical study of the fruits yielded triterpenoids (lupeol and α-amyrin). The cytotoxic evaluation was done on the methanolic extracts and selected compounds, lupeol, α-amyrin, lupeol acetate and (+)-catechin isolated from F. burtt-davyi stem bark and fruits. The… 
5 Citations
Antioxidant activity of the bioactive compounds from the edible fruits and leaves of Ficus sur Forssk. (Moraceae)
Ficus sur Forssk. (Moraceae) is a medicinal plant species found in Africa and the leaves are used in traditional medicine as a blood builder to boost iron levels for the treatment of anaemia, skin
Phytochemical profile and antiproliferative effect of Ficus crocata extracts on triple-negative breast cancer cells
TLDR
Extracts of F. crocata decreased the proliferation of MDA-MB-231 cells, with Dic-EFc having the strongest effect, and their potential use against triple-negative breast cancer is suggested.
Enhanced Anticancer Activity of Hymenocardia acida Stem Bark Extract Loaded into PLGA Nanoparticles
TLDR
The outcomes from this research showed that H. acida has anticancer activity as claimed from an ethnomedical point of view; however, a loss in activity was noted upon encapsulation, due to the sustained release of the drug.
Determination of Lupeol, a Cytotoxic Compound Against SW620 Cells in the Extracts of Ha-Rak Recipe
Ha-Rak (Benchalokawichian) is one of the famous Thai herbal recipes, which has been included in the National List of Essential Herbal Medicines of Thailand. The recipe contains the five herbal roots

References

SHOWING 1-10 OF 42 REFERENCES
Anticancer activity of lactuca steriolla growing under dry desert conditionof Northern Region in Saudi Arabia
TLDR
To discover the anticancer activity of the terpinoid compound isolated from terrestrial Saudi plants, the MeOH extract of the aerial parts of the plant lactuca steriolla family Asteraceae was in vitro investigated for cytotoxicity against HCT116, A549, HepG2 and MCF-7 cell lines, and resulted in vitro show high cytotoxic activity against breast cancer.
CHEMICAL CONSTITUENTS AND IN VITRO ANTIOXIDANT ACTIVITY OF CRUDE EXTRACTS AND COMPOUNDS FROM LEAVES AND STEM BARK OF FICUS BURTT-DAVYI.
TLDR
The results suggest that the plant can be used as a therapeutic agent in alternative medicine for oxidative stress related degenerative diseases.
Ceramides and cytotoxic constituents from Ficus glumosa Del. (Moraceae)
Chemical investigation of the stem bark of Ficus glumosa (Moraceae) yielded two new ceramides (2R,7E)-2-hydroxy-N-[(2S,3S,4R)-1,3,4-trihydroxyhexadecan-2-yl]hexacos-7-enamide and
In vitro antineoplastic effect of Ficus hispida L. plant against breast cancer cell lines
TLDR
The results have shown that the methanol extract exhibited antineoplastic activity against T47D cells, and may provide some benefits in the treatment of breast cancer.
Triterpenes and Cytotoxic Activity of Acokanthera oblongifolia Hochst. Growing in Egypt
TLDR
The in-vitro cytotoxicity of the total chloroformic extract and the main isolated triterpene compound was evaluated against three different human cell lines, hepatocellular carcinoma, breast adenocarcinoma and colon cell line.
Evaluation of anticancer activity of Debregeasia Salicifolia extract against estrogen receptor positive cell line
Crude methanol extract and fractions of Debregeasia salicifolia stem were examined for their anticancer activity. To determine anticancer activity, different concentrations of crude extract were
In vitro Cytotoxic Activity of Aqueous Root Extract of Althea kurdica against Endothelial Human Bone Marrow Cells (line k562) and Human Lymphocytes
TLDR
The traditional extract of A. kurdica roots showed in vitro cytotoxic effects on two different cell lines, Interestingly the IC50 value was higher in the normal human lymphocytes comparing to the Human Bone Marrow Cells, thus, the concentrations between 5 mg and 7.5 mg could be used for cancer treatment.
Effects of Ficus hirta Vahl. (Wuzhimaotao) extracts on growth inhibition of HeLa cells.
...
...