Cytotoxic activity of complexes formed as a result of interaction between tumor necrosis factor-α and α2-macroglobulin

Abstract

The conditions under which complexes are formed between tumor necrosis factor-α and α2-macroglobulin are examined in different molar ratios of ingredients with subsequent isolation of formed complexes using gel-filtration and testing of their cytotoxic activity. It is found that tumornecrosis factor-α binds with the activated (F-form) but not with the… (More)
DOI: 10.1007/BF02447131

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