Cytotoxic activity of Mycobacterium ulcerans.

  title={Cytotoxic activity of Mycobacterium ulcerans.},
  author={J K Read and C M Heggie and Wayne M. Meyers and Doreen Connor},
  journal={Infection and immunity},
  volume={9 6},
Although Mycobacterium ulcerans elicits extensive necrosis of human skin and subcutaneous tissue, the specific cause of the necrosis has never been elucidated. In an attempt to define a toxic substance, 18 strains of M. ulcerans were inoculated into mice, and the progress of each infection was observed and compared with infections of other mycobacteria, including M. cheloni, M. marinum, and M. bovis. Culture filtrates and viable organisms of each of these mycobacteria were inoculated onto… CONTINUE READING


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Buruli ulcer in Ghana.

British medical journal • 1971
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