Cytotoxic activities and effects of atractylodin and β-eudesmol on the cell cycle arrest and apoptosis on cholangiocarcinoma cell line.

@article{Kotawong2018CytotoxicAA,
  title={Cytotoxic activities and effects of atractylodin and β-eudesmol on the cell cycle arrest and apoptosis on cholangiocarcinoma cell line.},
  author={Kanawut Kotawong and Wanna Chaijaroenkul and Poonuch Muhamad and Kesara Na-Bangchang},
  journal={Journal of pharmacological sciences},
  year={2018},
  volume={136 2},
  pages={
          51-56
        }
}
Cholangiocarcinoma (CCA) is the cancer of bile duct with high mortality rate particularly in Thailand. The clinical efficacy of the standard chemotherapeutics remains unsatisfactory, and therefore, discovery and development of the new alternative drugs with high efficacy and tolerability is needed. The aim of the study was to investigate cytotoxic activity as well as the underlying mechanisms through which atractylodin and β-eudesmol exert their activities on CCA cell growth inhibition, cell… CONTINUE READING
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