Cytotoxic T-cell response to respiratory syncytial virus in mice.

  title={Cytotoxic T-cell response to respiratory syncytial virus in mice.},
  author={Charles R. M. Bangham and Martin J. Cannon and David T. Karzon and Brigitte A. Askonas},
  journal={Journal of virology},
  volume={56 1},
The role of the humoral and cellular arms of the immune response in protection against respiratory syncytial virus (RSV) infection and in the pathogenesis of the severe forms of this disease is poorly understood. The recent demonstration that some inbred mouse strains can be infected with RSV has opened the way to a detailed investigation of RSV immunity. We report here the finding of major histocompatibility complex-restricted, RSV-specific memory cytotoxic T cells in the spleens of BALB/c and… CONTINUE READING


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