Cytotoxic Sesquiterpene Lactones from Kauna lasiophthalma Griseb

@article{Maldonado2014CytotoxicSL,
  title={Cytotoxic Sesquiterpene Lactones from Kauna lasiophthalma Griseb},
  author={Eliana M Maldonado and Daniel Svensson and Stina Oredsson and Olov Sterner},
  journal={Scientia Pharmaceutica},
  year={2014},
  volume={82},
  pages={147 - 160}
}
Two new eudesmane derivatives (3 and 8) were isolated from the ethanol extract of the aerial parts of Kaunia lasiophthalma Griseb, together with 14 known eudesmane, germacrane, and guaiane sesquiterpenes, and four flavones. The structures and relative configurations of all the compounds were established by NMR spectroscopy and high-resolution mass spectrometry. The anticancer activity of sesquiterpenes 1, 3, 6–9, 11, 12, 14, and 16 was evaluated in vitro with the breast cancer cell lines… 
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