Cytotoxic Molecule-positive Epstein-Barr Virus-associated Peripheral T-cell Lymphoma in a 20-Month-old Child: A Case Report and Review of the Literature.

@article{Zhang2015CytotoxicME,
  title={Cytotoxic Molecule-positive Epstein-Barr Virus-associated Peripheral T-cell Lymphoma in a 20-Month-old Child: A Case Report and Review of the Literature.},
  author={Huina Zhang and Albert Kheradpour and Edward H Rowsell and Craig W. Zuppan and Lawrence M. Weiss and Jun Wang},
  journal={Journal of pediatric hematology/oncology},
  year={2015},
  volume={37 8},
  pages={e475-80}
}
Peripheral T-cell lymphoma (PTCL) is rare in children. Expression of cytotoxic molecules (CM) in nodal PTCL has unique clinicopathologic features, including an Epstein-Barr virus (EBV) association. However, CM+, EBV-associated PTCL is extremely rare in the childhood, with only 1 study having been reported to date, including both pediatric and adult patients. We report a case of CM+ PTCL in a 20-month-old boy with left neck lymphadenopathy as well as multiple visceral lesions. A biopsied lymph… CONTINUE READING