Cytotoxic Immunity in Peripheral Nerve Injury and Pain

@article{Davies2020CytotoxicII,
  title={Cytotoxic Immunity in Peripheral Nerve Injury and Pain},
  author={Alexander J. Davies and Simon Rinaldi and Michael Costigan and Seog Bae Oh},
  journal={Frontiers in Neuroscience},
  year={2020},
  volume={14}
}
Cytotoxicity and consequent cell death pathways are a critical component of the immune response to infection, disease or injury. While numerous examples of inflammation causing neuronal sensitization and pain have been described, there is a growing appreciation of the role of cytotoxic immunity in response to painful nerve injury. In this review we highlight the functions of cytotoxic immune effector cells, focusing in particular on natural killer (NK) cells, and describe the consequent action… Expand
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