Cytotoxic Effect of trans-Cinnamaldehyde from Cinnamomum osmophloeum Leaves on Human Cancer Cell Lines

  title={Cytotoxic Effect of trans-Cinnamaldehyde from Cinnamomum osmophloeum Leaves on Human Cancer Cell Lines},
  author={Shih-Hua Fang and Yerra Koteswara Rao and Yew-Min Tzeng},
  journal={International Journal of Applied Science and Engineering},
Quantitative determination of trans-cinnamaldehyde (TCA) was conducted by re- versed-phase HPLC from young and mature leaves, and leaf branches of Cinnamomum osmo- phloeum, a Taiwan endemic plant. The results showed that highest yield, 23.79 mg/g of TCA (the tree's age was three years) was obtained in the two year old mature leaves. In addition, cytotoxic and inhibitory effects of TCA was evaluated against selected human cancer cell lines such as Jurkat, U937, and normal cell lines primary… 

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