Cytotoxic Assay From Stem Bark Aglaia minahassae and Aglaia simplicifolia Against HeLa Cervical Cancer Cell Lines

  title={Cytotoxic Assay From Stem Bark Aglaia minahassae and Aglaia simplicifolia Against HeLa Cervical Cancer Cell Lines},
  author={Nunung Kurniasih and Hersa Milawati and Mohamad Fajar and Rizky Abdulah and Desi Harneti Putri Huspa and Unang Supratman},
Cervical cancer ranks as the 2 nd leading cause of female cancer in Indonesia. One of healing methods is chemotherapy, but this method still has many side e ects and also expensive treatment. Therefore, natural products discoveries need to be developed due to its important role as an alternative for anti- cancer drug. The aim of this research was to get IC 50 value from methanol, n -hexane, ethyl acetate, and n -buthanol from stem bark of A. minahassae dan A. simplicifolia . Stem bark of A… 


A number of promising new agents are in clinical development based on selective activity against cancer-related molecular targets, including flavopiridol, roscovitine, combretastatin A-4 phosphate, betulinic acid and silvestrol are inclinical or preclinical development.
Aktivitas Sitotoksik Ekstrak Etanolik Rimpang Temu Kunci (Boesenbergia pandurata) Terhadap Sel Kanker Serviks HeLa dan Sel Kanker Kolon WiDr
Low IC50 values showed that ethanolic extract of temu kunci is potential to be developed as chemoprevention agent on cervix cancer and colon cancer, however, its molecular mecahanism need to be explored.
Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms.
Two new lignans from twigs of Aglaia odorata
HPLC-guided separation of twigs of Aglaia odorata led to the isolation of eight lignans, including two new ones, 3′-methoxy-N-demethylrocaglamide (1) and 4′-O-demethyl-deacetylaglaxiflorin A (2).
Indonesian Tropical Medicinal Plants Diversity: Problems and Challenges in Identification
Describing Indonesian tropical medicinal plants diversity, its problems and challenges in identification, and suggesting on developing methodologies for effective and efficient identification are aimed at.
Uji Sitotoksisitas Ekstrak Metanol Daun Sisik Naga (Drymoglossum piloselloides Presl.) terhadap Sel Leukemia P388
Penelitian mengenai uji sitotoksisitas ekstrak metanol daun sisik naga ( Drymoglossum piloselloides Presl.) terhadap sel leukemia P388 telah dilakukan. Penelitian ini bertujuan untuk mengetahui
Taxonnomic Monograph of the Genus Aglaia Lour. (Meliaceae)
  • Kew Bulletin Additional Series XVI. HMSO,
  • 1992