Cytospin preparations are superior to common smears in the detection of monosodium urate crystals in low-cellular synovial fluids

@article{Robier2014CytospinPA,
  title={Cytospin preparations are superior to common smears in the detection of monosodium urate crystals in low-cellular synovial fluids},
  author={C Robier and Mariana Stettin and Franz Quehenberger and Miloslav Neubauer},
  journal={Clinical Rheumatology},
  year={2014},
  volume={33},
  pages={1797-1800}
}
In cases of gout with a low synovial fluid (SF) leukocyte count and atypical clinical presentation, such as in intercritical periods, the load of monosodium urate (MSU) crystals is frequently low, and thus, methods to improve the crystal detection may be beneficial. We compared the MSU crystal detection rates between cytospin slides and common smear preparations in low-cellular (<2,000/μl) SF samples of patients with gout. We determined the number of MSU crystals/15 high power fields (HPF) at… CONTINUE READING

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