Cytosolic phospholipase A2 group IVA influence on GM-CSF expression in human lung cells: a pilot study.

Abstract

BACKGROUND Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important mediator in the differentiation, maturation, and survival of inflammatory cells. It might play a significant role in the pathogenesis of asthma. We have shown previously that cytosolic phospholipase A2 group IV A (cPLA2alpha) is able to activate gene expression, through… (More)

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